Last year Corify Care closed the second year of the DIDIMO Project, Personalized Cardiac Digital Twin to Improve the Development of Medical Devices and Cardiac Anti-arrhythmic Treatments.
The goal of DIDIMO is to develop a personalized cardiac digital twin tool that combines patient-specific electrical and structural information into a mathematical model: DIDIMO (Greek word for "twin") that will serve to A) evaluate in-silico tens of therapeutic strategies in a personalized way and select the optimal treatment for each patient and B) accelerate pharmacological and medical device development by placing innovative technology in the hands of the industry to optimize clinical trials and obtain safer and more effective products.
Providing therapies tailored to each patient is the vision of precision medicine in the XXI century, enabled by (1) the increasing ability to capture extensive data about individual patients and (2) the increasing power of computers and algorithms to learn, reason, and build the 'digital twin' of a patient.
More than 10 million patients with cardiac arrhythmias across Europe would benefit from having a digital twin of their heart. Currently, the most effective treatment is cardiac ablation. Still, many patients (more than 60% of persistent atrial fibrillation -AF- patients, for instance) require several procedures, amounting to an excess of €13,5 billion of healthcare costs. The main reason for this low efficacy in treatments for arrhythmias is the lack of tools to identify the cardiac region that originates or maintains the arrhythmia in each patient. Success rates could be doubled if a personalized ablation strategy is performed thanks to cardiac digital twins.
DIDIMO project is constituted by Adas3D Medical, SL and CORIFY. We will collaborate with the ITACA and CMT groups of Universitat Politècnica de Valencia (UPV), and Hospital Clinic of Barcelona through IDIBAPS Institute.Grant PLEC2021-007614 funded by MCIN/AEI/ 10.13039/501100011033 and, as appropriate, by “ERDF A way of making Europe”, by the “European Union NextGenerationEU/PRTR”.